Detalhe da pesquisa
1.
Challenges and recent progress in drug discovery for tropical diseases.
Nature
; 559(7715): 498-506, 2018 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30046073
2.
Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasis.
Nature
; 560(7717): 192-197, 2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-30046105
3.
Author Correction: Cyclin-dependent kinase 12 is a drug target for visceral leishmaniasis.
Nature
; 619(7970): E48, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-37402863
4.
Mycobacterium tuberculosis Phe-tRNA synthetase: structural insights into tRNA recognition and aminoacylation.
Nucleic Acids Res
; 49(9): 5351-5368, 2021 05 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-33885823
5.
High-Throughput Screening Platform To Identify Inhibitors of Protein Synthesis with Potential for the Treatment of Malaria.
Antimicrob Agents Chemother
; 66(6): e0023722, 2022 06 21.
Artigo
em Inglês
| MEDLINE | ID: mdl-35647647
6.
Identification of a Proteasome-Targeting Arylsulfonamide with Potential for the Treatment of Chagas' Disease.
Antimicrob Agents Chemother
; 66(1): e0153521, 2022 01 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-34606338
7.
Compounds enhancing human sperm motility identified using a high-throughput phenotypic screening platform.
Hum Reprod
; 37(3): 466-475, 2022 Mar 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-35048946
8.
Preclinical candidate for the treatment of visceral leishmaniasis that acts through proteasome inhibition.
Proc Natl Acad Sci U S A
; 116(19): 9318-9323, 2019 05 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-30962368
9.
High-throughput phenotypic screening of the human spermatozoon.
Reproduction
; 163(1): R1-R9, 2021 12 27.
Artigo
em Inglês
| MEDLINE | ID: mdl-34882578
10.
Synthesis of a Series of Diaminoindoles.
J Org Chem
; 86(17): 11333-11340, 2021 09 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-34351743
11.
Ligand binding: evaluating the contribution of the water molecules network using the Fragment Molecular Orbital method.
J Comput Aided Mol Des
; 35(10): 1025-1036, 2021 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-34458939
12.
Clinical and veterinary trypanocidal benzoxaboroles target CPSF3.
Proc Natl Acad Sci U S A
; 115(38): 9616-9621, 2018 09 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-30185555
13.
Characterising covalent warhead reactivity.
Bioorg Med Chem
; 27(10): 2066-2074, 2019 05 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-30975501
14.
Optimisation of a key cross-coupling reaction towards the synthesis of a promising antileishmanial compound.
Tetrahedron Lett
; 60(18): 1243-1247, 2019 May 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-31057189
15.
Antitrypanosomal 8-Hydroxy-Naphthyridines Are Chelators of Divalent Transition Metals.
Antimicrob Agents Chemother
; 62(8)2018 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-29844044
16.
2,4-Diamino-6-methylpyrimidines for the potential treatment of Chagas' disease.
Bioorg Med Chem Lett
; 28(18): 3025-3030, 2018 10 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-30104093
17.
Automated design of ligands to polypharmacological profiles.
Nature
; 492(7428): 215-20, 2012 Dec 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-23235874
18.
Screening a protein kinase inhibitor library against Plasmodium falciparum.
Malar J
; 16(1): 446, 2017 11 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-29115999
19.
N-myristoyltransferase inhibitors as new leads to treat sleeping sickness.
Nature
; 464(7289): 728-32, 2010 Apr 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-20360736
20.
Characterization of a melamino nitroheterocycle as a potential lead for the treatment of human african trypanosomiasis.
Antimicrob Agents Chemother
; 58(10): 5747-57, 2014 Oct.
Artigo
em Inglês
| MEDLINE | ID: mdl-25022590